Selected Projects, Since 1999

Skin Cell Spray Grafting

(2016 – 2019)
Development of clinical skin stem cell isolation kits and skin stem cell spray devices enabling autologous skin cell spray grafting. Partners: RenovaCare Inc., New York, NY; Vector Asset Management, Vancouver, Canada, Charité, Berlin, Germany.

RepliCel Hair Stem Cell Isolation and Skin Injection Technologies

A biomedical engineering technology and a stem cell biotechnology evaluation of the RepliCel platform technologies.
Partners: RepliCel, Vancouver, Canada; University of British Columbia, Canada.

California Institute for Regenerative Medicine Liver Project

(2015 – 2018)
Development of clinical grade extracorporeal liver support system with human induced pluripotent stem cell-derived hepatic cells. Partners: University of Southern California, USA, CIRM, Los Angeles, USA; Medical Faculty Charité of the Berlin Universities, Germany.

The ATHENA Project

(2012 – 2016)
Multinational project supported by the US Defense Thread Reduction Agency on the development of a "Desk Top Human" for drug and toxic agent screening.
Partners: the Los Alamos National Laboratory (LANL); the Vanderbilt Institute; Berlin Charité consortium for miniaturized artificial organ reconstruction, Germany.

Technology Development Project "Bioreactors as in vitro Pharmakological Research System Replacing Animal Studies"

(2010 – 2011)
SCS as an R&D partner and developer of in vitro sysetms to culture liver cells. Partners: Karolinska Institute, Gothenburg, Sweden; Astra Zeneca, Gothenburg, Sweden; Charité, Berlin, Germany.

D-Liver: ICT-enabled Cellular Artificial Liver System, Incorporating Personalized Patient Management and Support

(2011 – 2015)
Multinational Project sponsored by the European Commission. Partners: University of Newcastle; CEA-Leti, Grenoble; CSEM Centre Suisse d'Electronoque et de Microtechnique; Fraunhofer Gesellschaft Germany, St. Ingbert; Stiftelsen Sintef, Norway; Charité – Medical Faculty of the Berlin Universities – Dept. of Experimental Surgery, Berlin, Germany.

Use of Innovative Hollow Fiber Capillaries in Wound Management

(2011 – 2014)
Research project sponsored by the German Government (BMBF). Partners: Membrana GmbH, Wuppertal (3M); Charité Experimental Surgery, Berlin, Germany; Excorlab GmbH.

DARPA Project "Continuous Red Blood Cell Production"

(2010 – 2011)
SCS as an R&D partner and supplier of a perfusion bioreactor to culture red blood cells. Partners: Celgene USA; The Automation Partnership (TAP)/ Sartorius Stedim; University of Pittsburgh, Mc Gowan Institute for Regenerative Medicine, Pittsburgh, PA.

Use of Growth Factors in Wound Treatment

(2008 – 2009)
Research project funded by the German Ministry of Economy. Partners: Biopharm GmbH, Heidelberg; Charité Experimental Surgery, Berlin, Germany.

Hybrid Tissue Technology in Burn Treatment and Transplantation Medicine

(2001 – 2005)
Research project funded by German Government (BMBF) and Investitionsbank Berlin. Partners: Unfallkrankenhaus Berlin / Burn Center Berlin; Charité Experimental Surgery; Biochrom KG (Merck), Berlin, Germany.

Evaluation of Wound Dressing Technologies

A technology biotechnological and cell biological evaluation on wound dressing products.
Partner: B.Braun, Melsungen, Germany.

Extracorporeal Liver Support

(2002 – 2004)
A technology Evaluation for Fresenius. Partners: Fresenius AG Germany; Charité Experimental Surgery, Berlin, Germany.

Liver Support Therapy with Immortalized Human Liver Cells

(1999 – 2004)
Research project funded by German Government (BMBF).
Partners: Hepavec AG, Berlin, Germany; Charité Experimental Surgery, Berlin; University of Bielefeld, Germany; University of Rostock. Germany.

EU Demonstration Project

(1999 – 2003)
Clinical extracorporeal liver support therapy with liver cells in bioreactors for patients in acute liver coma.
Partner: EU Commission, Brussels, Belgium; Charité, Berlin, Germany; University Hospital Clinic, Barcelona, Spain.